Get Expert Pet Advice Straight to Your Inbox

  • Get expert-backed advice on your pet's health.
  • Receive vet-reviewed tips for seasonal care.
  • Join a community committed to smarter pet care.
Petful

Dogs

  • Health & Care
  • Food & Nutrition
  • Training & Behavior
  • Breeds

Cats

  • Health & Care
  • Food & Nutrition
  • Training & Behavior
  • Breeds

Company

  • About Us
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • Takedown Policy

Contact

  • Contact us
  • 224 W 35th St. Ste 500, #549
    New York, NY 10001
Smart Pet Collective
  • webvet
  • petrecalls
  • telavets
  • vetstreet
  • mypetid

© 2026 Petful™. All Rights Reserved.

Petful
  • Reviews
  • Tools
  • About
  1. Home
  2. Dogs
  3. Pet Health
  4. A Drug-Free Answer to Your Dog’s Itchy Skin
DogsPet Health

A Drug-Free Answer to Your Dog’s Itchy Skin

Itch-free skin without drugs is a real possibility with the benefit of an immunotherapy vaccine.

Dr. Pippa Elliott, BVMS, MRCVS
Dr. Pippa Elliott, BVMS, MRCVS

BVMS, MRCVS

Jul 24, 2015· Updated Dec 16, 20243 min read
Happy dog beside Stella & Chewy's Raw Duck Dinner Patties
88 days left
Enter to Win
Stella & Chewy's
The Super Smiles Giveaway
Win $250

of premium raw food · Ends Aug 15, 2026

Enter Now
MyPetID
Free Forever
Meet your pet's AI.

Free digital ID. Records that follow your pet. Smart AI in your pocket.

Get Free Pet ID
  • Free AI chat assistance
  • Automatic vaccine reminders
  • Records saved forever
A Drug-Free Answer to Your Dog’s Itchy Skin

Don’t you just love a bichonwith a bouffant top-knot?

Little Annie is one such fashionista. This little dog with a big personality always has coordinated outfits with her mom.

In the winter, Annie wears a fuchsia quilted coat with matching collar and leash, and her mom wears a jacket accessorized with a handbag in the exact same shade. Only one thing marred this pair's couture perfection, and that was Annie’s paws.

Persistent Paw Licker

Annie is a persistent paw licker. In fact, she licked so much that her feet were rust-colored, which is obvious when the rest of her coat was snow white. These stained paws were somewhat at odds with the rest of her stylish appearance, but what was the reason for her licking habit?

Annie has atopy, an allergic reaction that causes itchy skin.

Annie had a workup and went on a hypoallergenic diet, and all the results pointed to her having specific allergies surrounding common grasses and tree pollens. We tried Annie on 2 types of medication, but the first made her gain weight and the second gave her a nasty tummy upset.

I was left scratching my head.

Vaccinate Against Itchiness

We decided to try Annie on immunotherapy injections. This treatment works on the same principle as vaccination in that it primes the immune system but without causing illness.

The patient receives regular injections of small amounts of the allergens to which she is sensitive. The treatment starts off with miniscule amounts so the body registers the allergen but doesn’t think it’s worth doing anything about it.

Over the following weeks, the dose is slowly nudged up -- the idea being to get the immune system used to the allergen but without priming it for a full-blown allergic reaction.

This means when the dog encounters the allergen for real, the immune system shrugs its shoulders and says, “So what?” and the dog doesn’t get itchy.

Immunotherapy

Immunotherapy is drug-free but requires a specialist lab to make a bespoke vaccine for each patient. This means identifying the substances the dog reacts to, by running either a blood test or a skin allergy panel.

After the initial “priming” injections, the dog receives 1 injection per month to keep topping up the protection. In Annie’s case, she had a panel of blood tests that rated her body’s immune reaction to a number of common pollens.

Annie was already regular with her parasite treatments, but this is doubly important for dogs with atopy. Why? Because flea saliva is a potent allergen, and it’s a rare dog who has atopy and doesn’t also react to flea saliva.

In this video, veterinarians discuss atopy in more detail:

Staying on Schedule

Annie's mom brought her in regularly for injections.

Because Annie had treats every time for being such a good girl with the injection, I became worried she was putting on weight. I took the opportunity to weigh her each visit.

Indeed, Annie’s waistline was one reason her mom wasn’t keen on steroids. The short time she was on them, Annie’s hunger was unstoppable, and her size ballooned.

For some dogs, the drug-free option of immunotherapy is the perfect answer to their itchiness problems, and happily this was the case for Annie. Within a few weeks of Annie starting therapy, her mom was delighted to point out Annie’s paws were once again snow-white. No more licking!

About Immunotherapy

Statistics suggest that around 4 out of 10 dogs respond completely to immunotherapy and don’t need other treatment.

Another 3 or 4 out of 10 partially respond, meaning they can reduce the amount of other medications they take (and if those drugs are steroids with side effects or other costly medications, the reduction matters).

However, immunotherapy is not a quick fix. If your pet has summer allergies, then the ideal time to start is in the autumn so the immune system gets trained over the winter when there are fewer allergens around.

If it’s mid-summer and you’re desperate for your dog to get relief, then conventional medications such as corticosteroids or new treatments such as cyclosporine (Atopica) or oclacitinib (Apoquel) will be needed to stop your dog from chewing himself to pieces.

Annie's Results

Our story has a happy ending. Annie continues to do well. Instead of monthly injections, they’re now once every 6 weeks, which is enough to keep her allergen protection ticking over -- not bad for a drug-free treatment when Annie would otherwise have required long-term medication.

vet-cross60p

This pet health content was written by a veterinarian, Dr. Pippa Elliott, BVMS, MRCVS. It was last reviewed Dec. 17, 2018.

Woman with dog checking pet health alerts on phone
Don't Guess When It Comes To Your Pet's Care

Sign up for expert-backed reviews and safety alerts all in one place.

Dr. Pippa Elliott, BVMS, MRCVS
About Dr. Pippa Elliott, BVMS, MRCVS

BVMS, MRCVS

Dr. Pippa Elliott, BVMS, MRCVS, is a veterinarian with nearly 30 years of experience in companion animal practice. Dr. Elliott earned her Bachelor of Veterinary Medicine and Surgery from the University of Glasgow. She was also designated a Member of the Royal College of Veterinary Surgeons. Married with 2 grown-up kids, Dr. Elliott has a naughty Puggle named Poggle, 3 cats and a bearded dragon.

Jump to Section
  • Persistent Paw Licker
  • Vaccinate Against Itchiness
  • Immunotherapy
  • Staying on Schedule
  • About Immunotherapy
  • Annie's Results
Related Articles
Pet Health
My Dog Ate a Grape: What to Do Immediately
Pet Health
Are Automatic Litter Boxes Safe for Cats? Risks and Benefits (2026)
Pet Health
The Delicate Subject of Dingleberries (or Pseudocoprostasis)

Don't Guess When It Comes To Your Pet's Care

Sign up for expert-backed reviews and safety alerts all in one place.

Woman with dog checking pet health alerts on phone
Don't Guess When It Comes To Your Pet's Care

Sign up for expert-backed reviews and safety alerts all in one place.

You Might Also Like

Concerned chocolate Labrador standing next to a tipped-over wooden bowl of spilled red grapes on a kitchen floor (emergency grape ingestion scenario)
Pet Health

My Dog Ate a Grape: What to Do Immediately

Feb 26, 2026
Grey tabby cat sitting peacefully beside a modern white domed automatic self-cleaning litter box in a warm sunlit modern home
Pet Health

Are Automatic Litter Boxes Safe for Cats? Risks and Benefits (2026)

May 17, 2026
Dingleberries
Pet Health

The Delicate Subject of Dingleberries (or Pseudocoprostasis)

Nov 19, 2025

Comments